The appearance of lymphatic vessels obstruction in lymphoscintigraphy of two breast cancer patients

Lymphoscintigraphy has been recognized as the modality of choice for lymph node staging of breast cancer patients. After intradermal injection of radiotracer, visualization of one or more sentinel lymph nodes in the axillary region and sometimes lymphatic vessels is expected. We report two cases of breast cancer who were referred to the nuclear medicine department for sentinel lymph node mapping before surgery. Unexpectedly, diffuse distribution of radiotracer and dermal backflow appearance was found. At final histology lymph node involvement and lymphatic vessels invasion was confirmed.