Effect of Selenium and Electrical Stimulation on Sperm Parameters and Spinal Cord Repair: A Rat Model of Spinal Cord Injury
Message:
Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Background

Selenium (Se) and Electrical stimulation (ES) play an important role in maintaining the integrity of various body functions after spinal cord injury (SCI).

Objectives

This study aimed to investigate the effect of Se and ES on the sperm parameters and the repair of the damaged spinal cord in a rat model.

Methods

A total of 50 male Wistar rats were randomly divided into five groups (n = 10 per each group, including control, sham, SCI, Se, and ES. After SCI in the T10 space, the BBB and Von Frey test were used to evaluate the motor and sensory functions. Six weeks after the treatment, the assessment of sperm parameters was done.

Results

The treatment with Se, compared to the SCI group, significantly increased the sperm concentration (38.66 ± 14.81 vs. 18.50 ± 7.02, P < 0.001), motility (55.00 ± 3.0 vs. 8.33 ± 1.16, P < 0.001) and viability (81.66 ± 8.16 vs. 19.16 ± 1.06, P < 0.001). ES compared to the SCI group, significantly increased sperm motility (60.00 ± 6.32 vs. 8.33 ± 1.16, P = 0.001) and viability (70.83 ± 9.70 vs. 19.16 ± 1.06, P < 0.001). Se and ES revealed no significant effects on sperm morphology (P > 0.05). A significant increase was observed in the BBB locomotor Score and Von Frey test in the SE and ES groups compared to the SCI group and between the Se and ES groups. However, no significant difference was observed between the Se and ES groups in the Von Frey test.

Conclusions

The effect of Selenium on sperm parameters and motor function was superior than that of the Electrical stimulation, but the effective effect on repairing the sensory function was the same.

Language:
English
Published:
Iranian Red Crescent Medical Journal, Volume:21 Issue: 9, Sep 2019
Page:
4
magiran.com/p2032304  
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یک‌ساله به مبلغ 990,000ريال می‌توانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
توجه!
  • حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران می‌شود.
  • پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانه‌های چاپی و دیجیتال را به کاربر نمی‌دهد.
دسترسی سراسری کاربران دانشگاه پیام نور!
اعضای هیئت علمی و دانشجویان دانشگاه پیام نور در سراسر کشور، در صورت ثبت نام با ایمیل دانشگاهی، تا پایان فروردین ماه 1403 به مقالات سایت دسترسی خواهند داشت!
In order to view content subscription is required

Personal subscription
Subscribe magiran.com for 50 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!