Effect of Aerobic Interval Training on Acylated Ghrelin, Peptide Tyrosine Tyrosine and Glucagon-Like Peptide-1 in Healthy Young Men

The aim of this study was to investigate the effect of aerobic interval training on acylated ghrelin, peptide tyrosine tyrosine (PYY) and glucagon-like peptide-1 (GLP-1) in healthy young men. Twenty male students with age 22.26±1.25 years old and BMI 23.2±1.4 kg/m2 were randomly assigned to the training and control groups. The training group completed a high intensity interval aerobic exercise training for 12 weeks. The training program consists of four minutes running periods on treadmill with intensity of 85-95%HRmax followed by three minutes of 65-75% HRmax rest active periods. The levels of plasma acylated ghrelin, PYY3-36 and GLP-1 were measured by ELISA method before and after eight- and 12-weeks trainings. In data analysis, was used the Mann-Whitney U test in order to compare the control and training groups and the Wilcoxon test in order to compare the training periods. The results showed that in the training group, levels of acylated ghrelin significantly (P=0.008) decreased after 12 weeks compared to the eight weeks. However, there were no significant changes in the acylated ghrelin, PYY and GLP-1 levels compared to the control group after eight and 12 weeks. Overall it seems appetite hormones alterations in young active males in response to aerobic interval trainings were not considerable, but a 12 weeks period of aerobic interval training may decrease appetite compared to the same training during eight weeks.