Evaluation of serum concentration of haptoglobin and amyloid A in the horses with piroplasmosis

Piroplasmosis is a protozoal disease that can cause acute inflammation in the horse. The disease is transmitted by ticks and spread worldwide. Measurement of acute inflammatory phase proteins is important in the diagnosis of inflammation from the disease. This study was conducted to evaluate serum Amyloid A and Haptoglobin levels in horses with pyroplasmosis and compare them with healthy horses. 19 horses with piroplasmosis (12 males and 7 females) were identified on horseback riding around Tabriz and Ardebil in the summer. From the livestock, after taking the history, blood samples were collected from the jugular vein and the serum was isolated. Also, 18 healthy horses (negative blood samples) were also sampled with the same age and nutritional and management status as the healthy group. In each blood sample prepared after serum separation, the serumicheptoglobin and amyloid A values ​​were measured on the basis of immunoassay and specific kits. The mean serumic amyloid A level in horses with piroplasmosis was higher than healthy horses, non significantly (p = 0.164). The mean serum haptoglobin increased in the patient group, significantly (p = 0.014). There was no significant difference between sex and age in serumic levels of these two parameters. The final result is that in piroplasmosis disease in the horse, the serumic levels of amyloid A and heptoglobin increase, and its measurement will be useful in the diagnosis and interpretation of the inflammatory process.