The Prophylactic Effect of Cuminum cyminum Extract on Gastric Residual Volume in Traumatic Patients under Ventilator Hospitalized in Intensive Care Unit

Increased Gastric residual volume (GRV) is one of the common problems in ICU.

The aim of this study was to determine the effect of cumin extract on gastric residual volume in patients with traumatic episodes hospitalized in ICU.

This double-blind randomized clinical trial was conducted on 60 patients traumatic hospitalized in ICU. Patients were randomly assigned to one of two groups: cumin (n = 30) and distilled water (n = 30). In the intervention group, 6 grams of cumin extract in 3 divided doses were given 50 drops in 30 cc of urban water at 3 times every 8 hours after. The remaining volume was recorded for up to 4 consecutive days and the data were compared in two groups. (IRCT: 201610297494N24).

Before the intervention, there was no significant difference between the mean GRV in the cumin group and placebo group (P = 0.63). Comparing the two groups of placebo and placebo, there was no significant difference in the amount of residual stomach in hospitalized patients with ICU on the first day (P = 0.13), but on the second, third and fourth days, this difference was significant between the two groups (p = 0.001).Comparing the two groups of intervention and placebo, the average volume of residual stomach before and during 4 consecutive days after intervention was significant (P = 0.001).

The results of this study showed that cumin extract was effective in decreasing residual stomach volume in hospitalized patients with ICU in comparison with placebo.