Investigation of Methamphetamine as a Stimulant with Side Effects and Methods of Synthesis and Impurities in any Way

The stimulants are materials that increase alertness and reduce physical and mental
fatigue. These drugs increase the activity of excitatory receptors and reduce the activity
of inhibitory receptors in the central nervous system. Methamphetamine, also known as
crystal, is a psychoactive substance. This drug is stimulating nerves and by a direct effect
on the brain, mechanisms cause joy and excitement in people. Methamphetamine in low to
moderate doses (5 to 30 mg) causes euphoria; excitement, increased heart rate, and blood
pressure, mydriasis, increased body temperature and decrease appetite. High but non-lethal
doses of methamphetamine cause mental disorders and psychotic symptoms, seizures,
and rhabdomyolysis. Cardiovascular toxicity of methamphetamine-induced hypertension,
arrhythmia, acute coronary syndrome and ischemic ventricular. The most important cellular
mechanisms involved in the damage caused by Methamphetamine are oxidative stress,
excitotoxicity, and mitochondrial damage. The synthesis of methamphetamine in illegal
workshops mainly of six methods which are based on the raw materials are divided into
two groups. Raw materials in the synthesis of methamphetamine are ephedrine and phenyl
propanol. In reduction, methods involve Birch reduction, Nagai and hydrogenation Rosenmund
ephedrine and pseudoephedrine are used as raw material, in Lockhart methods and amination
reduction methods based on phenyl propanol as raw material.