Comparison of metabolic syndrome components, inflammation and oxidative stress indices in normal weight obese and normal weight women: A case- control study

Message:
Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Background

Normal Body Mass Index (BMI)=18.5-24.9 kg/m2 and high Body Fat (BF), have been defined as Normal Weigh Obesity (NWO), which can increase the risk of Metabolic Syndrome (MetS) and cardiovascular diseases. The present study aimed to determine the association between NWO and MetS indicators, Insulin Resistance (IR), and inflammatory and oxidative stress indices in NW obese compared to normal weight women referring to Imam Reza medical center, Shiraz, Iran.

Methods

In this case-control study, 41 healthy NW obese Iranian women were recruited and compared to 45 healthy non-obese control subjects. Anthropometric features, body composition, blood pressure, inflammation and oxidative stress indices, fasting insulin, lipid profile, and blood sugar were measured. IR was also assessed by means of special formulas.

Results

The results showed a significant difference between the NWO and the control group regarding anthropometric measurements and body composition, including waist (P=0.008) and hip (P<0.001) circumferences, BF (P<0.001), skeletal muscle (P=0.03), protein (P=0.04), body cell mass (P=0.02), bone mass content (P=0.04), and arm circumference (P<0.001). All subjects had normal systolic and diastolic blood pressures. However, the NWO group showed significantly higher serum concentrations of triglycerides (P=0.02), total cholesterol (P=0.02), and C-reactive protein (P<0.001). On the other hand, the results of McAuley test indicated significantly lower insulin sensitivity in the NWO group (P=0.03). Besides, serum MDA concentration did not have a marked differences in both study groups.

Conclusion

Comparison of body composition and anthropometric indices between NWO and normal weight women demonstrated that counting just on BMI to distinguish the individuals who are at risk of metabolic disorders might fail to identify a large number of individuals who, despite having a normal BMI, present excess BF and are at a high risk of metabolic imbalances.

Language:
English
Published:
Journal of Health Sciences and Surveillance System, Volume:6 Issue: 3, Jul 2018
Pages:
116 to 122
magiran.com/p2078614  
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یک‌ساله به مبلغ 1,390,000ريال می‌توانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
توجه!
  • حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران می‌شود.
  • پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانه‌های چاپی و دیجیتال را به کاربر نمی‌دهد.
دسترسی سراسری کاربران دانشگاه پیام نور!
اعضای هیئت علمی و دانشجویان دانشگاه پیام نور در سراسر کشور، در صورت ثبت نام با ایمیل دانشگاهی، تا پایان فروردین ماه 1403 به مقالات سایت دسترسی خواهند داشت!
In order to view content subscription is required

Personal subscription
Subscribe magiran.com for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!