In this study, the effects of changes in environmental salinity on some biochemical parameters and body composition in yellowfin seabream (Acanthopagrus latus) were assayed. Fish adapted to salinity of 20 ppt, then suddenly introduced in experimental salinities including 5, 12 and 34 ppt. Each treatment was done in three replicates. In each replicate, 12 fishes with an average initial weight of 100± 10 grams per 300-liter tanks were placed. alues increased in group 12 and 34 ppt (P<0.05). A higher level of triglyceride and lower levels of high density lipoprotein were recorded in 34 ppt compared to other treatments (P<0.05). The proximate composition of body was affected by salinity as moisture was lower in 34 ppt in compare to other groups (P<0.05). In this study, A. latus survived without mortality in experimental salinities, but changes induced for osmoregulation in 5 ppt requires high energy consumption, which reduces the energy available to the fish.
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