Effects of Prenatal and Perinatal Factors on Nephrotic Syndrome Outcome

Nephrotic syndrome is a condition which can be influenced by pregnancy conditions.

Based on this, aim of this study was evaluation of perinatal and prenatal indices in nephrotic syndrome.

A case control study was done in 100 children with nephrotic syndrome. Perinatal and prenatal data were obtained, and for patients’ outcome determination, they had taken prednisolone for 4 weeks and syndrome types were determined based on responses to drugs as steroid responsive, steroid resistant, frequent relapse, and steroids dependent. At the end, information was entered into SPSS and analyzed.

Remission type children had a better outcome (No: 25) compared to others (No: 75) have a better status in prenatal and perinatal factors (P < 0.05). Gestational age (P value = 0.387), delivery type, diabetic nephropathy (P value = 0.007), passive smoking and neonatal jaundice have significant differences in groups.

Some of these factors have a significant effect in nephrotic syndrome outcomes that evaluated in this study.