Royal jelly Accelerate healing of acetate induced gastric ulcer in male rats

Abstract Background

Scientific reports suggest that bee products are useful for healing of wounds.


The healing potential of royal jelly on the acetic acid induced wounds healing in male rat’s gastric mucosa were studied.Materials: 96 male Wistar rats divided into in 4 groups includes: Control (without treatment), Omeprazole (20 mg/kgw), and Royal jelly (50, 200 mg /kgw). Gastric ulcer was induced in all rats with100% acetic acid. Treatment groups received omeprazole or royal jelly from 1nd to 14th day after acetic ulceration.  The histopathological parameters were evaluated on 4, 7, 10,15th days after ulceration.


 The administration of royal jelly significantly reduced depth of gastric lesion (p<0.05) and attuned histopathological changes compere to control group. The largest healing effect of royal jelly was on the 10 day of treatment, and at its higher used concentration (200 mg/kg).  


These findings supported that royal jelly has valuable effects on Gastric ulcer healing, and can used for peptic ulcer therapy.

Gastroenterology and Hepatology From Bed to Bench Journal, Volume:13 Issue: 1, Winter 2020
14 to 22  
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یک‌ساله به مبلغ 990,000ريال می‌توانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
  • حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران می‌شود.
  • پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانه‌های چاپی و دیجیتال را به کاربر نمی‌دهد.
In order to view content subscription is required

Personal subscription
Subscribe for 50 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!