Association between dietary inflammatory index and components of metabolic syndrome

Limited data are available on the association of Dietary Inflammatory Index (DII) withmetabolic syndrome (MetS),its components. The present study was conducted to investigate theassociation of DII with MetS,its components among Iranian adults.

A total of 404 subjects,aged 18 years or older,were included in the current cross-sectionalstudy. We used a validated,reliable 147-item food frequency questionnaire (FFQ) to assess dietaryintakes. Fasting blood sample was obtained to quantify glycemic indicators,lipid profile. MetS wasdefined based on the guidelines of the National Cholesterol Education Program Adult Treatment PanelIII (ATP III).

Mean age of study participants was 38.20±9.55 years. No significant association wasfound between DII,odds of MetS (odds ratio [OR]: 0.92,95% CI: 0.48-1.76). In terms of MetScomponents,a significant positive association was seen between DII scores,reduced levels of highdensity lipoprotein cholesterol (HDL-C) (OR: 2.29,95% CI: 1.32-3.97),such that after controlling forenergy intake,demographic variables,BMI,participants in the highest category of DII had 2.71times greater odds for having reduced levels of HDL-C (OR: 2.71,95% CIs: 1.34,5.47). There was noother significant association between other components of MetS,DII scores either before or afteradjusting for confounding variables.

We observed no significant association between DII,odds of MetS. However,higherscore of DII was associated with lower levels of HDL.