Investigation of Graft Survival of Kidney Transplantation in Transplant Patients of Shahid Hasheminejad Hospital during 2008-2013 (Iran)

Given the advances in treatment and use of new therapies in kidney transplantation, there is always a need to evaluate the survival of graft and patient and to investigate the effect of new therapies. Therefore, the purpose of this study was to assess the survival rate of kidney graft and patient in patients transplanted in Shahid Hasheminejad hospital during 2008-2013.

This retrospective study was conducted on 750 transplant patients. Using a checklist, demographic characteristics of recipients and donors, kidney failure (ESRD) characteristics, history of transplantation, transplantation source and its function, transplant rejection, and patient's status in last follow-up, were recorded. The data were entered into SPSS software version 23 and the survival rates of the transplanted kidney and the patient, was calculated using life tables and Kaplan-Meier analysis.

According to Kaplan-Meier analysis, the Mean survival time of the patients was 85 ± 1 month. The survival rate in patients aged over 40 years and graft survival rate in patients with unknown causes of ESRD and diabetes, were lower. The survival rate of transplanted kidneys in patients with DGF was lower than in patients with SGF or EGF. Sex, blood group, pre-transplantation dialysis, transplantation source, and donor sex had no effects on the survival of graft and patients.

The findings of the present study showed that the 7-year survival rate of the transplanted kidney and patient in patients who underwent transplantation, was 79% and 80%, respectively, and the mean survival time of graft and patient, were 84 and 85 months, respectively.