Study of Selenium Nanoparticles Synthesis and Investigation of its Effect Compared with Other Selenium Sources on the Blood Parameters Associated with the Liver Functional Index of Holstein Dairy Cow

Application of different source of minerals and their effect on metabolic performance a current issue in animal science and research centers.

The objective of this study was synthesis of selenium nanoparticles and to investigate its effect compared with other selenium sources on the blood parameters associated with the liver functional index of Holstein dairy cow.

This study was conducted in two phases: laboratory and farm. Oxidation-reduction chemical reactions were used to synthesize selenium nanoparticles. The formation and non-change of Se nanoparticles size were confirmed by particle size analyzer. In order to perform farm experiment, 6 dairy cows were allocated into three treatments and 2 replicates in a 3×3 Latin square experiment with 28 days change over the period. The animals were distributed to three treatment groups. Treatments (diets) were 1) control (sodium selenite source), 2) colloid sodium selenite and 3) selenium nanoparticles. Blood parameters associated with the liver functional index, including albumin, bilirubin and total cholesterol were measured in the present experiment. Also, dry matter intake of cows was recorded.

The blood plasma cholesterol of cows fed the colloidal sodium selenite was higher than cows fed the selenium nanoparticles (P-Value =0.01). The blood serum albumin (P-Value =0.03) and bilirubin levels (P-Value =0.04) were lower in group 3 compared with group 1. Dry matter intake was not affected by treatments.

According to the results of this experiment it seems selenium nanoparticles supplementation   improves blood parameters associated with the liver functional index, which can better improve immune system of dairy cows than two other sources of selenium.