Comparison of the effect of trigger of ovulation with HCG and HCG plus oxytocin on the biochemical pregnancy

Infertility is defined as not getting pregnant after 1 year of unprotected intercourse. Given the large area and high population of Sistan & Baluchestan province and many patients referring to the infertility center of Ali-ibn-e Abitaleb Hospital, this study was performed with aim to compare two methods of ovulation triggers for treatment of infertility in women with no ovulation.

This clinical trial was conducted on 100 infertile women (50 in each group) with infertility referring to gynecology clinic of Ali ibn-e Abitaleb Hospital of Zahedan  in 2017-2018. Patients were randomly assigned into two groups of HCG or HCG plus Oxytocin groups. The rate of pregnancy was evaluated. Data were analyzed by SPSS software (version 22) and Chi-square, independent t and Mann-Whitney test. P

According to the results of Chi-square test, frequency of pregnancy was significantly higher in HCG plus oxytocin group than HCG alone group (p=0.016).

HCG plus oxytocin significantly increases pregnancy rate in infertile women.