Anti-Malassezia IgE in Patients with Atopic Eczema Before and After Treatment with Ketoconazole Shampoo

Treatment of some fungi species would result in the improvement of atopic eczema.

In this study, the anti-Malassezia IgE in patients with atopic eczema before and after treatment with a ketoconazole shampoo was determined.

In this before-after investigation, 20 consecutive patients with atopic dermatitis referring to a teaching hospital in Tehran, Iran, in 2015 were enrolled. A ketoconazole shampoo was administered two times a week each time for 5 - 10 minutes. The treatment was used for two months and monthly evaluations were done. The total IgE level and anti-Malassezia IgE were compared at the beginning and the end of the study.

The results demonstrated that there was a statistically significant difference in the total Ig-E level and anti-Malassezia IgE before and after treatment with ketoconazole.

According to the obtained results in this study, it may be concluded that ketoconazole would result in decreased anti-Malassezia IgE and total IgE level in patients with atopic eczema