Histopathological effect of aflatoxin B1 on some internal tissues of rainbow trout (Oncorhynchus mykiss)

Present study was carried out to assess effects of aflatoxin B1 on different rainbow trout tissues. In the present study, 207 rainbow trout fingerlings with an average body weight of 9.67±0.2 g were reared for eight weeks in three distinctive treatments (control group, 25 and 50 ppb aflatoxin B1). At the end of the trial, various tissues of experimental groups were studied regarding probable histological alterations. Histological alterations due to dietary aflatoxin B1 exposure including hyperplasia and lamellar necrosis in the gill, necrotic and vascular changes in the brain along with inflammatory cell infiltration and necrotic changes in the intestinal and pyloric region were evident. The severity of pathologies was more pronounced in those fish received 50 ppb aflatoxin B1 content in comparison to the group fed 25 ppb toxin contaminated diet.