The Effects of an Herbal Mixture on the Clinical Symptoms of Women with Polycystic Ovary Syndrome

Polycystic ovary syndrome is the most common endocrine disorder in women. Multiple-drug treatments and prolonged treatments often cause patients to discontinue the treatment. Considering the side-effects of chemical drugs, the present study aimed to investigate the effects of the combination of cumin and fennel extract on the clinical symptoms of women with polycystic ovary syndrome.

This clinical trial was conducted on 70 patients with polycystic ovary syndrome, who were selected randomly from the patients referring to the teaching hospitals in Shahrekord, Iran. The patients were randomly divided into two groups of intervention and control. The intervention group received capsules containing fennel and black cumin, and the control group received placebo twice per day for four months. Before and after the intervention, the clinical symptoms of the subjects were evaluated in both groups. Data analysis was performed in SPSS.

In the intervention group, a significant reduction was observed in hirsutism, while the menstrual duration increased compared to the control group (P<0.05). However, these changes were not considered significant in the control group (P>0.05).

According to the results, the combination of fennel and cumin extract could effectively improve the clinical symptoms of the patients with polycystic ovary syndrome. Therefore, the herbal mixture could be used as a non-toxic medication for the treatment of these patients.