Prevalence of Underlying Diseases in Hospitalized Pa-tients with COVID-19: a Systematic Review and Meta-Analysis

In the beginning of 2020, an unexpected outbreak due to a new corona virus made the head-lines all over the world. Exponential growth in the number of those affected makes this virus such a threat. Thecurrent meta-analysis aimed to estimate the prevalence of underlying disorders in hospitalized COVID-19 pa-tients.

A comprehensive systematic search was performed on PubMed, Scopus, Web of science, andGoogle scholar, to find articles published until 15 February 2020. All relevant articles that reported clinical char-acteristics and epidemiological information of hospitalized COVID-19 patients were included in the analysis.

The data of 76993 patients presented in 10 articles were included in this study. According to the meta-analysis, the pooled prevalence of hypertension, cardiovascular disease, smoking history and diabetes in peopleinfected with SARS-CoV-2 were estimated as 16.37% (95%CI: 10.15%-23.65%), 12.11% (95%CI 4.40%-22.75%),7.63% (95%CI 3.83%-12.43%) and 7.87% (95%CI 6.57%-9.28%), respectively.

According to the find-ings of the present study, hypertension, cardiovascular diseases, diabetes mellitus, smoking, chronic obstructivepulmonary disease (COPD), malignancy, and chronic kidney disease were among the most prevalent underlyingdiseases among hospitalized COVID-19 patients, respectively