Shahrestani is the owner of the book nations and Nahl and interpretation of Mafatih-ol-Asrar and Masabih-ol-Abrar is in its interpretation of narrations prophet's family especially Imam J.Sadegh (PBUH)use has. He claims that in pars Mafatiol-Asrar have been taken of prophet's family. The purpose of this paper is analyse the degree of reading of these discussions with the narratives of the prophet's family especially Imam J.Sadegh (PBUH). This paper deals with analytical-descriptive method with the interpretation of "Mafatihol-Asrar and Masabihol-Abrar" , which investigates the issues of Quranic Sciences in Shahrestani's interpretation ,that each of these discusions are considered as a Quranic science, including: descending of Quran, generic and specific, firm and similar, abrogated and paid. In many cases, the content of Alasrar is influenced by prophet's family especially Imam J. Sadegh (PBUH) , the readings sometimes explicit and syntax is complete and in some parts are similarity of implicit and in some cases is minor.