Hashimotochr('39')s thyroiditis can be present with a localized palpable nodule though presentation as a hyperfunction "nodule" is extremely rare. The first case of Hashimotochr('39')s thyroiditis and hot nodule was reported in 1971 by warner.
We reported a 26-year-old hypothyroid woman in Hashimotochr('39')s thyroiditis background with a hyperactive thyroid nodule in both 99mTc and I131scintigraphy. The nodule disappeared after eight months sufficient thyroid hormone replacement therapy.
Toxic adenoma in hypothyroid patients can be resolved after the thyroxin replacement therapy.
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