In different verses of revelation, the guiding apparition of the Holy Quran is the best kind of guidance among various schools, thoughts, and ideologies. It can obviously be seen in these verses that the guiding plan of the Holy Quran is comprehensive and consists of all humans’ guiding needs. Some fourteenth-century interpretations applied the interpretation of the Quran to the Quran as the most important method for extracting the Quranic guiding strategies in terms of humans’ belief, social, moral, and educational issues, because, in the Quran, there are a number of the obstacles to and guides for humans’ growth and guidance in different aspects of their life. Al-Mizan fi Tafsir al- Quran and Fi Zelal al-Quran are among these interpretations that pay attention to the dynamics, trans-temporality, and trans-spatiality of guiding teachings of this holy book and explain it as a guiding miracle. Since the twentieth Surah of Quran talks about the most basic issues related to the beliefs such as origin and resurrection, prophecy, and the remembrance of God, with several instances, retells the different stages of Hazrat Musa’s life, and helps us reach a happy life through its belief, social, moral, and educational lessons, this analytical-descriptive study tries to clarify the most belief, moral, and educational teachings of Surah Taha from Allameh Tabatabaei’s and Seyed Ghotb’s viewpoints by using library written sources. The results show that these teachings are as follows: the explanation of monotheism, the purposes of sending the prophets, the necessity of resurrection, the Prophet Mohammad’s eternal miracle as a guide, the educational purposes of Musa’s story, the factors of humans’ aberration, the denial of fear and humility in the face of everyone, except God, humans’ intellectual and spiritual transformation after having faith in God, and the importance of remembering divine blessings and the ways to reach God’s satisfaction. It is necessary to say that these teachings are mentioned in Al-Mizan in more detail than Fi Zelal al-Quran.