The Effect of Aerobic Exercise on Indicators of Preptin, Irizine and Insulin Resistance in Obese Women

Obesity is one of the top 10 health problems in the world. The aim of the present study was to determine the effect of aerobic training on indices of perceptin, irizine and insulin resistance in obese women.

Thirty women were selected from obese women who referred to Ilam Health House in the age range of 30-45 years and were randomly divided into two groups of aerobic exercise (n = 10) and control (n = 10).  In the next stage and 24 hours before the start of the exercise, the individual characteristics of the subjects including age, height, weight and body mass index and the research variables (insulin resistance, Dpp4 and GLP-1) were measured in the pre-test and the training group. Then experiments performed aerobic exercise program for 8 weeks with intensity of 60-75% of maximum heart rate and 3 days per week for 30-45 minutes. The variables were measured again 24 hours after the last training session. Dependent t-test, two-way ANOVA and Bonferroni post hoc test were used for data analysis.

The results showed that aerobic training had effect on the levels of peptin, irizine and insulin resistance in obese women. Exercise, time, and the interactive effect of exercise and time have effect on preptin, irizine, and insulin resistance in obese women (p=0.001). There was also a significant difference between pre-test and post-test on one hand and exercise and no practice on the other (p=0.001).

According to the findings of this study, it is recommended to use aerobic exercise to reduce weight and minimize the negative effects of obesity in obese women.