Comparison of the effect of aerobic and resistance training on glucagon-like peptide-1 and insulin resistance in obese women with type 2 diabetes

The purpose of this study was to compare the effects of aerobic and endurance training on GLP-1 and insulin resistance in obese women with type 2 diabetes.

Thirty diabetic women aged 35-50 years, members of Saveh Diabetes Association, voluntarily participated in the present study and randomly divided into three groups of control (n=10), aerobic exercise (n=10) and resistance training (n=10). 24 hours before the start of the exercise protocol, individual characteristics and blood sampling were measured in the pre-test. Then the aerobic and resistance training groups performed their own training program for eight weeks (3 sessions per week and each session lasted 45-60 minutes). After eight weeks and 24 hours after the last training session individual data and blood samples were measured and analyzed using one-way ANOVA at p < 0.05.

The present study showed no significant difference between the effects of the two training methods on insulin resistance (P=0.922), but there was a significant difference between the effects of the two training methods on GLP-1 values (P=0.001).

Aerobic and resistance training can decrease appetite and weight control in obese women with type 2 diabetes by increasing     GLP-1. Aerobic training also seems to be more effective than resistance training.