Effect of Two Exercise Modalities on Some Liver Enzymes and Lipid Profile of Adolescents with Fatty Liver

The risk for nonalcoholic fatty liver (NAFLD) disease is directly related to the body mass index, with obese children being most at risk for NAFLD. The main aim of this study was to evaluate the changes in some liver enzymes and lipid profile of adolescents with fatty liver, following a selected school based and high intensity interval training. Thirty adolescent boys (aged11-14year) with obesity (based on ≥95th percentile of body mass index and age growth chart) and clinically defined as NAFLD disease were divided equally into the high intensity interval training (BMI; 26.51±1.83kg/m2, n=10), and selected school-based exercises (BMI; 26.69±2.45kg/m2, n=10). Hepatic ultrasonography, VO2peak, lipid profile, insulin resistance, AST and ALT levels of subjects were measured before and after the SBE (45-60 min. selected exercise and games) and HIIT (36-40 min Running at 100-110 maximum aerobic speed) protocols. ANCOVA statistics was used to analysis of data and results showed that there was a significant increase in VO2peak of groups after exercise intervention (P=0.001). Also, there were significant reductions in insulin resistance (P=0.01), triglyceride, alanine amino transferase and aspartate amino transferase levels in both groups (P=0.01). HDL levels increased significantly only in SBE group (P=0.048), but there were no significant differences between LDL levels of groups (P=0.250). Therefore, we concluded that both selected school based and high intensity interval training protocols were equally effective in improving some health parameters in children with obesity and fatty liver.