Comparative pathologic Study of Effect of Cold atmospheric Plasma and Ultraviolet Radiation on Staphylococcus aureus Infection in Diabetic Rats

The use of UV and cold atmospheric plasma improves the healing process significantly in compare with normal healing process. Comparative evaluation of histopathology and histomorphology of ultraviolet radiation of cold atmospheric helium plasma on a full-thickness Staphylococcus aureus infected wound in diabetes induced rats with alloxan40 male Wistar diabetic rats with intraperitoneal injection of alloxan at a dose of 120 mg / kg bodyweight with infected full thickness wounds with 1 ml of suspension containing 108 CFU / ml Staphylococcus aureus in 1 cm diameter have been divided into two groups of treatment with cold atmospheric helium plasma and UV radiation.The treatment groups were treated for 21 days with cold plasma and ultraviolet radiation for three minutes/day and the results have been evaluated histopathologically and Histomorphology, and statistical analysis of the SPSS system. Cold atmospheric helium plasma and UV Light have a positive effect on the presence of inflammatory cells, collagen formation, and the epithelial cells healing. The final conclusion Cold plasma and UV light plays a positive role in wound healing, and CAP is much more effective in wound healing.