The Correlation between Epicardial Adipose Tissue Thick-ness and Severity of Coronary Artery Disease; An Echocar-diographic Evaluation

Epicardial adipose tissue (EAT), as a visceral adipose tissue, is associated with various cardio-metabolic risk factors, such as fasting plasma glucose, systemic blood pressure and serum low-density lipopro-tein. Using EAT thickness as a cost-efficient assessment tool for stratifying the risk of coronary artery disease(CAD) is still controversial.

We enrolled 250 consecutive patients who underwent coronary angiogra-phy during 2016 and gathered their demographic. Echocardiographic examinations were performed in the leftlateral decubitus position and EAT thickness was measured in standard parasternal long-axis (PLAX) and apicalfour chamber views.

250 patients including 156 men (mean age: 57.66) and 94 women (mean age: 61.19)were enrolled. Two vessel disease (2VD) and three vessel disease (3VD) were significantly associated with hyper-lipidemia (P: 0.04), CKD (Chronic Kidney Disease) (P: 0.001), diabetes mellitus (P: 0.001) and smoking habits (P:0.001). Also, EAT thickness in PLAX view (P<0.001), and not four chamber view (P: 0.136), was significantly asso-ciated and correlated with increased involvement of coronary arteries in catheterization.

AlthoughEAT thickness in PLAX view was significantly correlated with 2VD and 3VD, this correlation was not strong andthe accuracy of this approach needs further evaluation.