Medical futility is one of the most common controversial topics in medicine, medical ethics, and philosophy of medicine. Every day, doctors are dealing with patients who are in a condition that must have a decision about requested futile treatment with their own beliefs, opinions, and different demands. This is an important issue that must be taught during teaching courses. Therefore, it is good to provide general policies for teaching how to make the best decision, establishing better communication between doctors and patients, and maintaining their Autonomy. On the other hand, with the interference and expansion of humanistic and holistic attitudes in the treatment of patients, it must be considered that at all treatment levels, especially decisions related to end-of-life, it is better to involve this point of view in our policies. In the present article, we tried to give a general conclusion of general policy and present standards for a humanistic policy by analyzing various countries’ policies and expressing their bugs.