Association between Anatomic Configuration of Throm-bosis with Clinical Symptoms and Risk factors in AdmittedPatients with Deep Vein Thrombosis

Deep vein thrombosis (DVT) is prevalent and challenging for physicians. Previously, the clinicalsymptoms of DVT are different based on the location of the thrombosis. In this study, the anatomic location ofthrombosis and its relation with clinical symptoms and DVT risk factors were investigated.

In this ret-rospective study, the hospital documents of 204 patients with acute lower extremity DVTs in Shohada-e-Tajrishhospital were reviewed from April 2020 to February 2021. The diagnosis was confirmed using Doppler ultra-sound. Based on the location of the thrombosis, the patients were divided into four groups: unilateral proximalgroup (UPG), bilateral proximal group (BPG), unilateral distal group (UDG), and ipsilateral proximal and distalgroup (IPDG). Finally, the frequency of risk factors and symptoms were compared between the groups.

In this retrospective study, 204 patients with the diagnosis of acute lower extremity DVTs at the time of hospi-talization or during hospitalization were studied. The mean±SD age of the patients was 57.1±19.2 years (range:12-98 years). Of these, 114 (55.9%) were men and 90 (44.1%) were women. There were 174 patients in UPG, 16 inBPG, 5 in UDG and 9 in IPDG. In total, 97.5% of the patients had proximal thrombosis while only 6.9% of themhad distal thrombosis. The incidence of different limb circumferences was significantly higher in UPG and IPDGcompared to BPG and UDG (P<0.05). There was no statistically significant difference between groups in termsof other symptoms and risk factors.

Most of the DVTs were found in the proximal veins of the lowerextremities. It seems that these DVTs are more likely to create edema compared to others and in unilateral casesmay result in different circumferences of the lower limbs. But there was no significant association between otherclinical signs of DVT including limb pain, edema, erythema, palpitations, and shortness of breath with throm-bosis location. Also not significant association between DVT risk factors and the location of thrombosis werefound.