Preparation of acridine orange-MWCNT modified electrode for voltammetric detection of dopamine in the presence of ascorbic acid

Acridine orange supported on multi-walled carbon nanotube (MWCNT) is used for modification of carbon-paste electrode. The studies show that acridine orange efficaciously immobilized in the matrix of the electrode by applying nafion/MWCNT composite under the ultrasonic condition. The results of voltammetric experiments demonstrate that the prepared electrode has an effective response to DA and AA and a relatively big anodic peak separation (nearly 368 mV) is obtained for these compounds. Good sensitivity and selectivity and very low detection limit (0.03 µM) makes the modified electrode very effective in the manufacture of simple devices for the concurrent detection of dopamine in the presence of ascorbic acid in clinical and pharmaceutical preparations.