Outcomes and Challenges associated with In vitro Fertilization in Women with Polycystic Ovary Syndrome: A review study
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Article Type:
Review Article (دارای رتبه معتبر)
Abstract:
Introduction

Polycystic ovary syndrome (PCOS)is the most common endocrine disorder in women of childbearing age.There are many challenges regarding the quality of oocytes in these individuals.Therefore, this review study aimed to investigate the consequences and challenges associated with in vitro fertilization in women with polycystic ovary syndrome.

Materials and Methods

For related studies, the Persian SID and Magiran databases and Pubmed, Scopus, Elsevier, Weily online library, Sciences Web of Science databases and Google Scholar search engine were used for the period 1990–2019. To obtain all articles in Persian and English,the keywords of Polycystic ovarian syndrome, in vitro fertilization, Polycystic ovarian morphology, IVF outcome,Oocyte donation,Oocyte competence,Pregnancy,and their Persian equivalent are used separately or as possible combinations. From 450 articles, 17 were eligible and selected for this study.

Results

The results of various studies suggesting major challenges in this group of women including gonadotropins need and hormone-related changes, ovarian hyperstimulation syndrome (OHSS), clinical pregnancy rates, pregnancy outcomes and the risk of miscarriage, the quality of oocytes in women with polycystic ovary syndrome undergoing in vitro fertilization and the issue of egg donation in this group of women. However, fetal loss, clinical pregnancy and live birth rates are no different from other women.

Conclusion

Due to concerns about pregnancy in women with PCOS, closer monitoring of these pregnancies is important, it also appears that the presence of PCOS in donors does not affect the rate of pregnancy or implantation and the number of embryos transferred in ovarian donation programs. As a result, women with PCOS should not be excluded from egg donation programs.

Language:
Persian
Published:
Journal of Sabzevar University of Medical Sciences, Volume:28 Issue: 3, 2021
Pages:
359 to 371
magiran.com/p2331197  
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