Predictors of Testis Cancer Mortality in Iran
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Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Introduction

Testis cancer is a rare cancer that afflicts young men. although the incidence of testis cancer isincreasing, the mortality rate is decreasing. This study examines the mortality of testicular cancer and its re-lationship with the human development index and its components in Iran during 2005-2015.Materials and

Methods

Data of patients with testis cancer were collected from the Office of National Cancer Registry in theMinistry of Health and Medical Education (MOH&ME) during 2005-2015. An additional telephone survey wasconducted by trained interviewers to collect data, including survival status, demographic characteristics, ageof cancer diagnosis and other clinical profiles. Kaplan-Meier survival rates were calculated according to demo-graphic characteristics, economic status, and residential area and socioeconomic status (SES). All the analyseswere done using STATA software, version 14 (StataCorp. 2015).

Results

From 2005 to 2015, 5886 testicularcancer cases were diagnosed among men in all age groups. Most patients (73.9%) were 15–49 years of age atthe time of diagnosis, 26.1% were 50 years of age or older. Seminoma was diagnosed among 46.78% of the pa-tients and non-seminoma among 42.28%. Factors which had impact on survival rate were age (P=0.001), tumorhistology (P=0.02, hazard ratio=1.23[0.98-1.38]) and TNM stage (P=0.001, hazard ratio=1.2[0.92-1.28]). Patientswho got married at the time of diagnosis more likely presented at earlier stages and had better overall testiscancer-specific survival than patients who were single, separated, widowed, or divorced (P=0.002, hazard ratio1.27[1.09-1.49]). Testis cancer mortality rate was significantly higher in patients who did not graduate from highschool and significantly higher in patients who were tenants (P=0.057, hazard ratio =1.132[0.996-1.28]).

Conclusion

Testis cancer mortality is decreasing in Iran. Age, TNM stage and histology, and marital and economicstatus were factors influencing mortality rate.

Language:
English
Published:
Men's health journal, Volume:5 Issue: 1, Winter 2021
Page:
32
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