The Effect of High Intensity Interval Training and Intermittent Fasting on Gene Expression VEGF in Cardiac Muscle Tissue Obesity Male Rats

The purpose of the present study was to investigate the combined effect of high intensity interval training and intermittent fasting on vascular endothelial grow factor gene expression in cardiac muscle tissue of obese male rats.

  A total of 22 male Wistar rats perch overall high fat diet for 12 weeks. Afterward were random divided into 4 groups (1) control (CO), (2) HIIT (three session for six week, 80 to 95% MRT), (3) IF (three days for six week ,12h) , HIIT & IF( received both protocol for six week). The Real- Time -PCR was used to measure VEGF gene expression. For analysis data used one way ANOVA and LSD significant p<0/05.

Results showed that no significant different between groups on gene VEGF expression (p>0/52).

Calculation:

 Our result showed that in subjected obese, HIIT + IF and HIIT and IF not significant on VEGF gene expression in cardiac muscle tissue male rats.