Short-term effect of apple vinegar on blood pressure, pulse pressure, and heart rate in healthy people: Randomized clinical trial- a linear mixed model analysis

Article Type:
Research/Original Article (بدون رتبه معتبر)
Background and objective

Apple vinegar is a fermented product prescribed for hypertension in Persian medicine. This study aimed to evaluate the short-term effect of oral administration of apple vinegar on systolic and diastolic blood pressure, pulse pressure, and heart rate in healthy individuals.

Materials and methods

This study was conducted on 40 healthy people. On test day, control group drank 200 ml water 4 h after breakfast, while test groups drank 200 ml water containing 22, 28, and 34 g apple vinegar. Blood pressure was measured just before intervention and also after intervention every 15 min for 2 h. Heart rate measurement was done before and after intervention. Pulse pressure was calculated as difference of systolic and diastolic blood pressures every time.

Results and conclusion

Our results showed no significant relationship between consumption of apple vinegar and systolic blood pressure. In the test group administered 22 g apple vinegar, pulse pressure and diastolic blood pressure decreased significantly after 75 min. According to linear mixed model, changes in systolic blood pressure score were not significantly affected by groups, but it was significantly affected by time (p = 0.037). In addition, interaction of time and low-dose apple vinegar group for diastolic blood pressure and pulse pressure were significant (p = 0.005 and p = 0.008, respectively). Higher amounts of apple vinegar showed no significant effect. This study revealed that apple vinegar could decrease diastolic blood pressure and pulse pressure in healthy people in short-term use. Considering there is no side-effect for apple vinegar by the studied amounts and also its potential in modulation of blood pressure, evaluation of its effects in hypertensive patients is recommended for further studies.

Human, Health and halal Metrics, Volume:3 Issue: 1, Winter-Spring 2022
1 to 11  
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یک‌ساله به مبلغ 1,390,000ريال می‌توانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
  • حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران می‌شود.
  • پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانه‌های چاپی و دیجیتال را به کاربر نمی‌دهد.
In order to view content subscription is required

Personal subscription
Subscribe for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!