COVID-19 has become a global problem. In this case study, the experiences gained from disease control in rural areas are reported.

An observational study was done in 2020 in Sistan and Balochestan, the largest province with most rural areas in the southeast of Iran.

After identification of the first patient of Covid-19 in a rural area, three measures were taken including: 1. Diagnosis, screening and treatment of the disease (Incident command post was established and the village was completely quarantined, etc.; 2. Intersectoral coordination for epidemiological management (limiting traffic for people and any gathering); and 3. Identification of any Covid-19 positive cases. The results of these measures showed that after quarantining the village and performing the mentioned actions, the number of patients decreased, and the disease was controlled.

Quarantine of the contaminated rural area and people’s traffic routes is one of the most important measures in controlling Covid-19.