Drug-induced esophagitis and helpful management for healthcare providers

In recent decades, the number of cases developing drug-induced esophagitis (DIE) has been identified to an increasing extent, which shows the significance of detecting medicines capable of causing this adverse reaction. This study aims to provide an updated review on recent case reports of DIE, evaluate the possible mechanism of this side effect, and provide helpful management. Data was gathered through searching three databases, including PubMed, Medline, and Cochrane. Seven drug categories were evaluated, including antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs), cardiovascular medicines, bisphosphonates, chemotherapeutic agents, miscellaneous agents, and supplements. According to our findings, retrosternal pain, heartburn, odynophagia, and dysphagia are the typical symptoms. In most cases, DIE is a self-limiting side effect that can resolve by removing the causative agent and supportive therapy.