The effect of high intensity interval training (HIIT) with portulaca Oleracea supplementation on serum levels of liver enzyme in rats with non-alcoholic fatty live disease

The aim of presenet study was survey the Effect of Portulaca Oleracea Supplementation with High Intensity Interval Training (HIIT) on Serum Levels of Liver Enzyme in Rats with Non Alcoholic Fatty Liver (NAFLD).

For this purpose, 25 male Wistar rats randomly divided into 5 groups: healthy control (n = 5), fatty liver control (n = 5), supplement. (N = 5), HIIT (n = 5) and HIIT+ supplement (n = 5). To induce NAFLD, rats were fed a high-fat diet for 12 weeks. Portulaca oleracea supplement at a dose of 400 mg/kg was given to the respective groups. The HIIT training protocol was performed for 8 weeks, 5 sessions per week with 90% of maximum speed. Plasma ALT, AST and ALP levels were measured by photometric methods. For data analysis, one-way ANOVA and post hoc Tukey tests were performed at a significance level of P˂0.05.

AST levels in HIIT training grouP (P=0.007) and supplement+HIIT (P=0.005) was significantly lower than the control grouP. However, despite the decrease in plasma AST levels in the supplement grouP compared to the fatty liver control grouP, this difference was not statistically significant (P=0.052). ALT level in the supplement grouP (P=0.038), HIIT (P=0.047) and HIIT+supplement (P=0.021) was significantly lower than the fatty liver control grouP. There was no significant difference between serum ALP levels of study groups after 8 weeks of HIIT training and portulaca oleracea supplementation (P=0.657).

Base on these results probably Portulaca Oleracea Supplementation with HIIT can be used as a complementary and non-pharmacological therapy in people with NAFLD.