Frequency and Pattern of Bacterial Antibiotic Resistance in Blood Culture Samples of Hospitalized Patients in Besat Hospital in Hamadan (2010-2020)

In recent years, resistance to antibiotics and the emergence of different strains of resistant bacteria have been of grave concern to the World Health Organization and all those working in the field of health. The aim of this study was to determine the frequency and pattern of bacterial antibiotic resistance in blood culture samples of hospitalized patients in Besat Hospital in Hamadan.

This descriptive cross-sectional study was conducted over a period of 10 years on all patients referred to Besat hospital in Hamadan with sepsis symptoms.

In this study, 1790 patients with positive blood culture were studied. The mean age of the patients was 24.81 years. 58.9% of the subjects with positive blood cultures were male. The majority of patients (38.4%) were hospitalized in the ICU. 48.8% of gram-negative bacteria and 49.1%-gram positive were reported. The most common isolated bacteria were staph aureus, Escherichia coli, Epidermidis staph. The highest resistance was to cefixime (70.6%) and cefpodoxime (67.5%) and the highest susceptibility to vancomycin (98.5%), piperacillin tazobactam (71.7%) and meropenem (70%).

The resistance of bacteria to available antibiotics in Besat Hospital in Hamadan is considerable and worrying and shows a serious risk of antibiotic resistance in Hamadan city, so it shows the necessity of serious interventions and reviewing the prescribing and consumption of antibiotics.