Public or citizen participation in safeguarding and running a government is one of the main constituents of Islamic political and social system. The Islamic Republic of Iran, manifesting a religious government in modern times, represents public participation in different political and social arenas to which the Grand Leader Ayatullah Khamenei has paid special attention and given special status. Given the fact that the Islamic Revolution has taken the second step (in its course of development), it seems to be necessary to acquaint with the position of public participation in continuing the Islamic Revolution. Drawing upon documentary, library, and Internet research methods and content analysis, this research aims to explain the extent to which the public participation may exert its effect on the continuation of the Islamic Revolution of Iran as far as the Grand Ayatullah Khamenei’s thought is concerned. The findings of the research indicate that, in Ayatullah Khamenei’s thought, the public participation in two political and social realms is the most important constituent in relation to the continuation of Islamic Revolution. According to him, the reliance of the Islamic Revolution of Iran on the permanent public participation can be surely taken to have been an important factor in neutralizing (nullifying) the enemies’ plot and their satanic plans against the Islamic Revolution during the past decades and a main cause of the continuation of the Islamic Revolution and a secret behind what prevents the decline of it.