The purpose of this research is to investigate the impact of human resource management on organizational innovation based on knowledge management. This research is descriptive and correlational. The statistical population includes employees and managers of the headquarters centers for the provision and development of welfare services in Tehran. According to Cochran's formula, the sample size was 109 people.

The researcher used a simple random sampling method to distribute the questionnaires. In order to obtain and collect information, Nonaka and Takeuchi (1995) knowledge management questionnaires, Bosley and Weil (2002) human resource management and Mirmiran model organizational innovation (2013) questionnaires were used. The reliability of the questionnaires was obtained using Cronbach's alpha method, 0.95, 0.91 and 0.97, respectively. Also, in order to test the hypotheses, the structural equation modeling method was used, and for descriptive data analysis and factor analysis, 22 spss and 3smart pls software were used.

The results indicate that human resource management combined with knowledge management has been effective on the organizational innovation of Tehran welfare development and supply centers. Also, human resource management has had a significant impact on organizational innovation and knowledge management.

This research, by increasing and applying knowledge by human resources management in Tehran welfare, has promoted organizational innovation and as a result, improved the effectiveness of services to the society, and the integration of knowledge in performance has been recommended by the management of human resources in Tehran welfare.