Fluorescence imaging is being used in a variety of new surgical uses. Many innovative fluorescent probes and imaging plans are also being advanced as part of the technology. The Low-pH insertion peptide (pHLIP) technology may offer numerous methods for progressively managing urinary tract cancers. For diagnosis and transurethral resection of bladder cancer, pHLIP-Indocyanine green (pHLIP-ICG) has been used inside the bladder, and pHLIP-amanitin has been utilized to inhibit the growth of bladder tumor cells.