Central Ossifying Fibroma in mandible: A Case Report with aggrasive behavior review of differential dragwsis

Central Ossifying Fibroma is a benign bone neoplasm. It has been categorized under fibro-osseous lesions and has significant growth potential that exact etiology is not known. According to studies it has a periodontal ligament origin. It is more prevalent in women and mandibular premolar and molar area. The lesion generally occurs in the third and fourth decades of life. Tumor removal by surgery or curettage are suitable treatment and its recurrence rate is reported to be between 0 to 28%. Most of the time the prognosis of the lesion is optimal nevertheless in some cases, malignant transformation has been reported.

Case Report:

 A 25-year-old woman was referred for dental treatment. The CBCT view demonstrated an ill-defined radiolucent-radiopaque lesion in right mandibular body, lack of lamina dura of the lower right canine tooth and destruction of the buccal and lingual cortex of that area. The lesion was removed by osteoctomy. In microscopic view, the histopathological profile of central ossifying fibroma was observed without evidence of malignant changes. Follow up of the patient after 6 months indicated complete healing and bone formation at that site.

It seems, ossifying fibroma can havd ivvassive feature in radio graphy and mimic malignant lesions. So, microscopic evaluate of all sections is important.