The effect of aerobic training and cinnamon extract gavage on adiponectin gene expression in liver and fat tissues of male rats fed by high fat diet

 Adiponectin with properties similar to exercise increases glucose uptake in muscle and decreases glucose production in the liver. Cinnamon has modulating properties against oxidative stress, blood sugar and obesity. Therefore, considering the effect of exercise training on adiponectin gene expression, the effect of high-fat diets on obesity and the effects of cinnamon on weight loss, the present study seeks to answer the question whether six weeks of aerobic exercise and cinnamon extract on adiponectin gene expression in Fat and liver tissues and the mass of these tissues have different effects in male rats fed with a high-fat diet.

 The present study was conducted in the form of a multi-group research project with a control group the average of the research variables among the groups were compared using one-way analysis of variance and Bonferroni supplementary test and independent t-tests and two-way analysis of variance at the significance level p ≥ 0.05 for all tests with the aim of determining the differences between the groups.

 The results showed the effect of high-fat diet on adverse changes in adiponectin gene expression in adipose tissue and liver, body weight and weight of adipose tissue and liver. Performing aerobic exercise alone, consuming cinnamon extract alone and the interaction of aerobic exercise and cinnamon extract caused favorable changes in the expression of adiponectin gene in adipose tissue and liver and the weight of adipose tissue and liver compared to the high-fat diet group.

 It seems that from the desirable and accepted physical activities and sports exercises on the Adipose tissue and liver, maybe some food intakes such as cinnamon supplement extract combined with sports exercises have synergy with useful exercises.