Prevalence of hyponatremia in hospitalized patients with coronavirus disease 2019; a multicenter study

In patients with coronavirus disease 2019 (COVID-19), the prevalence of hyponatremia has been reported with varying outcomes.

The aim of this study was to evaluate the prevalence of hyponatremia in hospitalized patients with COVID-19.

 Patients and Methods:

In this multicenter cross-sectional study, information about hospitalized patients with COVID-19 admitted between March 2020 and September 2020, including age, gender, and serum levels of sodium, creatinine, and potassium, as well as blood urea nitrogen (BUN), was analyzed, while P value level less than 0.05 was considered significant.

A total of 667 hospitalized patients with COVID-19 were enrolled in the study, of which 54.4% were male. The median age of patients was 63 years old. About 39.4% of patients had hyponatremia on admission day. More than 80% of patients had mild hyponatremia. The median age of the hyponatremia group was significantly higher than that of eunatremia group.

Our data showed that hyponatremia is observed in hospitalized patients with COVID-19 and is often mild.