A narrative review for evaluation of muscarinic receptor type-3 (MR3) in oral lichen planus patients

Oral lichen planus (OLP) is a persistent, inflammatory, mucocutaneous skin condition that often affects the oral cavity. The purpose of this narrative review research was to investigate muscarinic receptor type-3 (MR3) in OLP patients.

In order to perform this research, papers and scientific reports pertinent to the subject at hand were searched for utilizing specialized keywords in national and worldwide databases. The requisite final papers were then analyzed using the inclusion and exclusion criteria, and their findings were retrieved.

The amount of stimulated and unstimulated salivary flow, as well as the levels of MR3, were significantly reduced in patients with OLP compared to healthy persons. In addition, the data demonstrated that the prevalence of xerostomia in OLP patients was more than in healthy people.

Based on the results, it can be concluded that OLP patients have low salivary flow rate and lower level of MR3 and these patients suffer from xerostomia.