USE OF PRODUCTS EXTRACTED FROM BLOOD TO DESIGN BIOACTIVE STRUCTURES IN REGENERATIVE MEDICINE
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Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Background & Aim

Nowadays, according to the advances in medical science, blood products are considered as one of the important biological tools. In this regard, the use of blood-derived biomaterials in reconstructive medicine to repair a variety of tissues has expanded. One of these products is based on platelet separation, which is obtained by different processing techniques and is used alone or in combination with a variety of synthetic or natural structures. These platelet products contain a large number of growth factors that play key roles in the process of tissue repair and regeneration. The purpose of this study was to investigate the importance of these products in the repair of different body tissues.

Materials & Methods

This study is a review one that was conducted by electronic search in PubMed and EMBASE databases from 2000 to 2021 with keywords such as platelet⸲ growth factors⸲ stem cells and regenerative medicine.

Results

Findings from studies show that blood-derived biomaterials can be extracted by different techniques, and these products have different types of growth factors such as VEGF, PDGF, EGF, and TGF-β, which can contribute to faster tissue regeneration alone or in combination with other substances.

Conclusion

Studies show that blood-derived platelet products can facilitate and accelerate the healing process of various tissues. They can also help advance therapeutic goals.

Language:
Persian
Published:
Journal of Medical Science Studies, Volume:33 Issue: 8, 2023
Pages:
610 to 620
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