Evaluating the Effects of Camellia Sinensis (Green Tea) and Teucrium Polium Extracts on Salivary Streptococcus Mutans Levels in Children
Article Type:
Research/Original Article (دارای رتبه معتبر)

Statement of the Problem:

 Camelia Sinenis or green tea (GT) and Teucrium polium (TP) are known to have a great antimicrobial potential on salivary Streptococcus mutans (S. mutans).Their efficacy should be examined compared to the gold standard antimicrobial agents.


To evaluate the effects of Camelia Sinenis or green tea (GT) and Teucrium polium (TP) extracts in comparison with chlorhexidine gluconate (CHG) on salivary S. mutans levels.

Materials and Method

This double-blinded randomized clinical trial study was conducted on 90 preschool children aged 4 to 6 years and assigned randomly (simple randomization) to three groups as GT, TP, and CHG. Unstimulated saliva samples were then collected in three times as before application of agents, after half an hour, and after one week. To determine S. mutans levels, quantitative polymerase chain reaction (qPCR) technique was additionally utilized. Statistical analysis was also fulfilled using Shapiro-Wilk test, Friedman test, Chi-square test, paired sample t-test, repeated measures analysis of variance (ANOVA), and Mann-Whitney U test at a significance level of 0.05.


The results of this study established a significant difference between mean salivary S. mutans levels after administration of the three compounds. Although the mean of S. mutans levels reduced significantly following the application of CHG and TP after half an hour, the mean salivary S. mutans levels in the group receiving GT declined in a significant manner only one week later (p< 0.05).


The results of this study indicated that GT and TP extracts had considerable effects on salivary S. mutans levels compared with CHG.

Journal of Dentistry, Shiraz University of Medical Sciences, Volume:24 Issue: 1, Mar 2023
19 to 27
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