Primary Osseous Lesions of the Jaw in Iranian Population: A Study Based on Biopsy Material Over a 19-year Period
Intraosseous pathological lesions of the jaw include a wide range of benign to aggressive or malignant lesions with different clinical and histopathological characteristics and require various treatments. This study was designed to assess the frequency and characteristics of primary jaw lesions in a defined group of an Iranian population.
In this retrospective study, 6676 biopsy reports from the Oral and Maxillofacial Pathology Department, Shahid Beheshti University of Medical Sciences, were assessed. In cases with primary jaw lesions, other variables such as age, gender, location of lesions, and microscopic diagnosis were recorded. The lesions were categorized into “benign /malignant” and “inflammatory” /“non-inflammatory” groups. Chi-square, Kruskal-Wallis, and Fisher exact were used for statistical analysis.
In total, 395 (5.91%) cases (63.70% female, 36.29% male) with a mean age of 32.37±16.94 had a primary osseous lesion. About 74% of the lesions were found in the mandible with posterior predilection. Fibro-osseous lesions (28.72%), central giant cell granuloma (22.45%), and osteomyelitis (9.13%) were the most common histopathologic diagnoses. The most common malignant tumor was osteosarcoma (8.61%). Of the total lesions, 10.2% were inflammatory lesions. The most common lesions in children and adolescents were fibro-osseous lesions (24.7%), central giant cell granuloma (24.7%), and simple bone cysts (18.8%).
The main findings of this study were similar to those of most previous studies in different countries. Fibro-osseous lesions and central giant cell granuloma were the most common primary osseous lesions of the jaw in older adults and children with a female predilection. Malignancies included about 9% of all lesions.
- حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران میشود.
- پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانههای چاپی و دیجیتال را به کاربر نمیدهد.