Preparation of Polyhydroquinolines Using Nano Cerium (IV) Oxide/Zinc Oxide as a Catalyst

Message:
Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Polyhydroquinolines are crucial compounds with a very wide range of biological functions such as vasodilation, anti-atherosclerosis, liver protection, and anti-diabetic. It is also used in the preparation of drugs such as nifedipine, nicardipine and Lacidipine. The common method of synthesis of polyhydroquinolines is one-step condensation reaction of Dimedone, aldehydes with ethyl acetate and ammonia in the presence of various catalysts such as MCM-41, molecular iodine, bread yeast, etc. Most of these methods have disadvantages such as low gain, high reaction temperature, long time. In this research, cerium oxide / zinc oxide nanoparticles have been reported as a very effective and economical catalyst for the four-component and one-pot reactions of polyhydroquinolines using the reaction of Dimedone, Aryl halide, ethyl acetoacetate and ammonium acetate.
Language:
English
Published:
Journal of Applied Organometallic Chemistry, Volume:2 Issue: 2, May 2022
Pages:
74 to 80
magiran.com/p2641539  
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یک‌ساله به مبلغ 1,390,000ريال می‌توانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
توجه!
  • حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران می‌شود.
  • پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانه‌های چاپی و دیجیتال را به کاربر نمی‌دهد.
In order to view content subscription is required

Personal subscription
Subscribe magiran.com for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!