Effects of Corona Pandemic on Maternal-Neonatal Outcomes and Vaccination of Pregnant Women: A Narrative Review Study

Corona is a highly contagious respiratory disease. Pregnant women are more susceptible to viral respiratory infections. On the other hand, there is limited information on vaccination of pregnant women, so this review was conducted to investigate the relationship between maternal-neonatal outcomes and vaccination of pregnant women.

A present narrative review study was performed from late 2019 to September 2021 by collecting information from Magiran, SID, Library Cochrane, Science Direct, Scopus, PubMed and, Google scholar Web of Science databases, and using the English and Persian keywords “Delivery”, “Pregnancy”, “Vaccine”, “SARS-COV-2”, “COVID-19”, “Neonatal”, “Outcomes”, and “New-born”. Finally, 28 studies were included in the study with inclusion criteria.

Adverse obstetric and neonatal outcomes increase in sufferers in the second half of pregnancy. Common maternal consequences include cesarean section, premature birth, abortion, tachycardia, and premature rupture of the amniotic sac, and common neonatal consequences include effects on fetal brain development, increased risk of autism, and neurological problems. Also, maternal vaccination by transferring antibodies from the placenta to the fetus makes the baby immune.

Although pregnancy is not known as a factor in corona disease, with the focus on the consequences for both mother and neonate, self-care education is important. If possible, vaccination programs should target pregnant women early in pregnancy or before fertilization.