The effect of 8 weeks of aerobic training on changes in AST, ALT and metabolic indices of postmenopausal women with type 2 diabetes

Article Type:
Research/Original Article (دارای رتبه معتبر)
Introduction and Purpose

Liver enzymes are among the clinical biochemical parameters of liver function in muscle training, and aspartate aminotransferase (AST) and alanine aminotransferase (ALT) enzymes are indicators of liver damage in sports activities. Therefore, this study aimed to investigate the effect of 8 weeks of aerobic training on changes in aspartate aminotransferase, alanine aminotransferase, and metabolic indices in postmenopausal women with type 2 diabetes.

Materials and Methods

The current research is semi-experimental and was implemented with a pre-test and post-test design. 40 postmenopausal women with type 2 diabetes with an average age of 55-60 years were randomly divided into two groups aerobic exercise (20 people) and control (20 people). The aerobic training program was implemented for 8 weeks, five sessions a week for 60 minutes with an intensity of 50-75% of the reserve heart rate. ALT and AST levels as well as fat profile factors were measured in the pre-test and post-test. The data were analyzed by covariance analysis using SPSS version 22 software.


The results of the present study showed that in the aerobic training group, compared to the control group, the level of ALT and AST decreased significantly (P<0.05). In the aerobic training group, the level of HDL showed a significant increase compared to the control group (P<0.05). Also, the amount of triglyceride, cholesterol, and LDL in the aerobic training group was significantly reduced compared to the control group (P<0.05).

Discussion and Conclusion

It seems that doing aerobic exercises plays a significant role in improving or reducing liver diseases in patients with type 2 diabetes, But more studies are needed to reach a single treatment strategy and the most effective way.

نشریه ورزش و علوم زیست حرکتی, Volume:15 Issue: 2, 2023
99 to 107  
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یک‌ساله به مبلغ 1,390,000ريال می‌توانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
  • حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران می‌شود.
  • پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانه‌های چاپی و دیجیتال را به کاربر نمی‌دهد.
In order to view content subscription is required

Personal subscription
Subscribe for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!